Up All Night is switching formats from single-camera to multi-camera. The series has also changed showrunners multiple times. Now the show will have to recast. The series star Christina Applegate has decided to leave the show, Deadline reports. NBC is allegedly still determined to proceed with the show, which has yet to film any of its multi-camera episodes, and is considering Lisa Kudrow as a replacement for Applegate. May we humbly suggest that NBC think outside the box and consider recent Suburgatory guest star The Cancellation Bear for the role?